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The Phase 2 trial also included a meta-analysis benchmark: a 2025 systematic review and meta-analysis of 3 RCTs involving 878 patients found a mean body weight reduction of 14.33% versus placebo, with a BMI reduction of 5.38 and waist circumference reduction of 10.51 cm

Both medications require a prescription from a doctor, or a telehealth company like Hims or Hers

Food tracking reveals hidden calorie creep that stalls progress

Technically yes, but practically it creates a contradiction

and Ashley Sullivan, the executive producers behind the new documentary Breaking Big Food: How the American Food System Went Rotten and How It's Being Revived