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It can be administered at any time of day, with or without meals

However, it did not significantly change CRP levels, a common marker of general inflammation

On the other hand, changes in total cholesterol, LDL-cholesterol, and HDL-cholesterol levels were not statistically significant ( 3.4 The role of Spirulina in the immune system The immune system has a complex structure consisting of innate and adaptive immune mechanisms to protect the body against microorganisms and harmful pathogens ( Clinical studies have shown that using Spirulina as a feed supplement improves antioxidant biomarkers, including inflammatory and anti-inflammatory cytokines, and enhances growth performance, intestinal health, and immunity in fish and poultry

That pattern is not unusual within the wider incretin research category, where gastrointestinal tolerability is often one of the most closely monitored safety areas

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