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In the Phase 2 clinical trial (NEJM, 2023), retatrutide was administered subcutaneously at doses ranging from approximately 0.5 mg to 12 mg per week, with dose escalation under close medical supervision
Will any of my current medications need to be adjusted
Hormone variations (menstrual cycle, menopause status) can create weekly fluctuations in women that are less apparent in men, but total trajectory by week 48 is similar between genders
The impact of these drugs on other aspects of health must be monitored
These effects get stronger as the dosage increases
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