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The medication is category X in pregnancy, meaning known fetal harm outweighs any potential benefit
[3] FGF21 Analog Pegozafermin Pegozafermin is an investigational FGF21 analog engineered with glycoPEGylation technolog y designed to recapitulate the activity profile and prolong the half-life of the native FGF21 hormone, which may address underlying metabolic issues that drive liver and cardiometabolic diseases, such as MASH and SHTG
Originally developed to support blood glucose regulation in individuals with type 2 diabetes, these medications are now widely discussed for their effects on appetite, body weight, and metabolic health
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