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7 Discussion Current MASLD management primarily relies on lifestyle interventions, including weight reduction, dietary modification, and physical activity ( This review has systematically summarized evidence suggesting that L-carnitine exerts multi-targeted actions against MASLD pathogenesis by promoting lipid metabolism, improving insulin sensitivity, stabilizing hepatocyte function, and inhibiting inflammatory and fibrotic signaling pathways

It plays a role in gene expression and helps improve mitochondrial function

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Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity. Nature Hong, S., et al

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