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Strengths and limitations This is the first study to investigate the causal relationship between GLP-1RAs and arrhythmias using MR analysis, effectively addressing confounding factors and reverse causality

Losing and maintaining more than 10% of body weight is associated with significant reductions in obesity-related complications, including hypertension, type 2 diabetes, and heart disease

however, a more severe overdose can aggravate the injury and reduce and delay monocyte recruitment leading to impaired regeneration [107]

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Five islets per group were incubated at 37 C for 2 h in the low-glucose buffer, before the supernatants were collected and stored until analysis