Efficacy and safety of once-weekly semaglutide versus once-daily insulin glargine as add-on to metformin (with or without sulfonylureas) in insulin-naive patients with type 2 diabetes (SUSTAIN 4): A randomised, open-label, parallel-group, multicentre, multinational, phase 3a trial
Others got stuck in the digestive tract
Gong et al., 2024)
16 Figure 3: Risk of OACs in patients on GLP-1s versus patients on insulin Conclusion GLP-1s, initially developed to help manage and treat diabetes and later used to treat obesity, are now showing significant potential to help prevent and treat CVD, mental health disorders, liver and kidney disorders, neurodegenerative disorders, addiction disorders, and cancer
It actually increased new bone formation along the outer layer of bone (the periosteum), which strengthens the bone structure