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reported that LKB1 mutation in KRAS mutant lung adenocarcinoma confers a glutamate enriched phenotype in TME, and this feature was associated with CD8 + T cell activation against PD-1, whereas treatment with the glutaminase inhibitor CB-839 inhibited CD8 + T cell expansion and activation

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Semaglutide enhances glucose-dependent insulin secretion and suppresses inappropriate glucagon release, but these effects build gradually

H&E Staining The experiment was conducted according to the instructions of the HE staining kit (Solarbio, G1120)

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