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Although no significant change was observed in the bone formation marker P1NP, the semaglutide group showed a significant increase in the bone resorption marker CTX and a reduction in areal BMD at both the lumbar spine and total hip

12 in 1998 suggests that TJs, chiefly responsible for regulating paracellular permeability, are formed primarily by the newly identified claudin family of proteins

CSMC viability assay Freshly isolated CSMCs were cultured in 96-well plates at 110 5 cells/well

therefore, systemic steroids (prednisone 40 mg once daily) were initiated for the grade 2 irAE and ICIs were held