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A rigorous 2018 double-blind, placebo-controlled trial by Koozehchian et al
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EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS), Mortensen A, Aguilar F, Crebelli R, Di Domenico A, Dusemund B, Frutos MJ, et al: Re-evaluation of glutamic acid (E 620), sodium glutamate (E 621), potassium glutamate (E 622), calcium glutamate (E 623), ammonium glutamate (E 624) and magnesium glutamate (E 625) as food additives
When the amount of tyrosinase is reduced, the melanin formation process is also prevented, leading to brighter skin and less darkening