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In addition to these desirable effects, RK stimulating IGF-1 can also inhibit inflammation via stimulation of IL-10 production, reducing the overall visible redness seen in KP [15]

doi: 10.1016/j.ijbiomac.2025.143989 127 ZhangHLiuXZhengYZhaXElsabaghMZhangYet al

congenital anemia from fetal blood loss (P61.3) D50.1 Sideropenic dysphagia Kelly-Paterson syndrome Plummer-Vinson syndrome D50.8 Other iron deficiency anemias Iron deficiency anemia due to inadequate dietary iron intake D50.9 Iron deficiency anemia, unspecified D51 Vitamin B12 deficiency anemia Excludes1: vitamin B12 deficiency (E53.8) D51.0 Vitamin B12 deficiency anemia due to intrinsic factor deficiency Addison anemia Biermer anemia Pernicious (congenital) anemia Congenital intrinsic factor deficiency D51.1 Vitamin B12 deficiency anemia due to selective vitamin B12 malabsorption with proteinuria Imerslund (-Gr?sbeck) syndrome Megaloblastic hereditary anemia D51.2 Transcobalamin II deficiency D51.3 Other dietary vitamin B12 deficiency anemia Vegan anemia D51.8 Other vitamin B12 deficiency anemias D51.9 Vitamin B12 deficiency anemia, unspecified D52 Folate deficiency anemia Excludes1: folate deficiency without anemia (E53.8) D52.0 Dietary folate deficiency anemia Nutritional megaloblastic anemia D52.1 Drug-induced folate deficiency anemia Code first (T36-T50) to identify drug D52.8 Other folate deficiency anemias D52.9 Folate deficiency anemia, unspecified Folic acid deficiency anemia NOS D53 Other nutritional anemias Includes: megaloblastic anemia unresponsive to vitamin B12 or folate therapy D53.0 Protein deficiency anemia Amino-acid deficiency anemia Orotaciduric anemia Excludes1: Lesch-Nyhan syndrome (E79.1) D53.1 Other megaloblastic anemias, not elsewhere classified Megaloblastic anemia NOS Excludes1: Di Guglielmo's disease (C94.0) D53.2 Scorbutic anemia Excludes1: scurvy (E54) D53.

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