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Additionally, histological assessment involved Tyrosine Hydroxylase (TH) staining in the substantia nigra to evaluate the integrity and potential restoration of dopaminergic neurons, with evaluations performed at 1 month and 3 months post-lesion

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They also highlight the need for future clinical trials to more conclusively determine the dose and duration of GLP-1 receptor agonist-based treatments in patients addicted to different types of substances, including amphetamines, opioids, and benzodiazepines