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While direct cortisol measurements were not specifically reported in the published safety trials, the comprehensive metabolic monitoring across 900+ participants showed no clinically significant hormonal changes, and the mechanism of action provides no pathway for cortisol stimulation
Older adults may aim to maintain B12 levels as absorption naturally declines with age
However, vitamin B12 is an essential vitamin and requirements are increased during pregnancy
A doctor can look at both situations to guide you
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