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Lancet Diabetes Endocrinol 2022;10:193206.ArticlePubMed 50
2019 Apr;37(2):175-181
Reviewed by Dr
The peptide retains activity in human gastric juice for more than 24 hours, tolerates pH from 1 to 11, and resists multiple proteolytic enzymes, properties that derive from the high proline content (four of fifteen residues) and the absence of cleavage-prone motifs
(5) Doxycycline has a comparatively long half-life of 16-22hrs and so is often dosed once or twice a day
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