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Pure R-ALA degrades at room temperature, is sensitive to heat and light, and can polymerize clumping into larger, inactive molecules at temperatures above 115120F (4649C).42 These issues make it difficult to manufacture and store

Mice were divided into various groups by computer-generated randomization and then housed and labeled in individual cages

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Additionally, the safety profile of the prodrug nanosystem, and its potential effects on rice yield and quality were also explored