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Its also associated, in addition, with obstructive sleep apnea (OSAS), non-alcoholic fatty liver disease (NAFLD)/metabolic-associated fatty liver disease (MAFLD), osteoarthritis, gastro-esophageal reflux disease, malignancies (gastrointestinal, liver, breast, and endometrial cancer), and mental health issues, especially in young people
The tripeptide structure gets largely broken down by digestive enzymes before absorption
Weight loss drugs cause gastroparesis, or delayed stomach emptying, which increases the risk of aspiration during anesthesia
The results showed statistically significant but clinically modest weight loss (2kg average advantage over placebo at the 1mg oral dose over 23 weeks)