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The current analysis showed consistent reductions with semaglutide in the risk of MACE versus placebo across baseline eGFR and UACR subgroups, which is in line with a meta-analysis that evaluated CVOTs showing that GLP-1RAs reduced the risk of MACE versus placebo, regardless of baseline eGFR [7]

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Lu X, Zhang H, Zhang N, Dong C, Ji H, Yu J, Ban Z, Yan R, Zhang T, Chen C, Jiang Y (2023) Effects of ozone treatment on gene profiling involved in ASA-GSH cycle in postharvest cantaloupe