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Evaluation of the safety, pharmacokinetics and pharmacodynamic effects of subcutaneously administered PT-141, a melanocortin receptor agonist, in healthy male subjects and in patients with an inadequate response to Viagra
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GLP-1 acts primarily on the hypothalamic arcuate nucleus (POMC/NPY neurons) to regulate energy homeostasis and metabolic set-pointit's the 'background thermostat' for caloric balance
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