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Despite these promising findings, current evidence remains largely preclinical
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10.1007/s13277-015-3619-4 13 ChenL.ZhangJ.FengY.LiR.SunX.DuW.et al
2.5 Quality assessment and risk of bias In line with PRISMA guidelines, the assessment of methodological quality was conducted to evaluate the strength of evidence, recognising that methodological limitations may introduce bias
These combined effects are particularly intriguing for orthopedics because many musculoskeletal injuries (Achilles tendon ruptures, rotator cuff tears, chronic tendinopathies) occur in precisely those areas where blood flow is limited and healing is frustratingly slow
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