Primes clinical insights report outlines where we are today and how things are shaping up for the future, demystifying trends like GLP-1s and supporting a whole-person approach to sustainable weight management
Studies have shown that Complex I activity is diminished in both post-mortem brain tissue and peripheral blood cells of PD patients ( Previous studies have shown that mitochondrial dysfunction related to PD can be caused by various factors, including mitochondrial bio-genetic defects, increased ROS production, mitophagy defects, transport disorders, electron transport chain dysfunction, mitochondrial dynamics changes, and mitochondrial calcium imbalance
4.14 The Chinese Clinical and Preclinical Long Tail Two early-clinical Chinese programs round out the Phase 1 picture: DYX116 (Jiangsu Deyuan Pharmaceutical, Phase 1 initiated April 2025) and HEC-007 (Sunshine Lake Pharma, Phase 1 initiated August 2025)
Shariq AS, Brietzke E, Rosenblat JD, Barendra V, Pan Z, McIntyre RS
About this article Cite this article Sridhar, V.S., Limonte, C.P., Groop, PH