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Both work to increase growth hormone levels, but in slightly different ways
Compared with conventional GLP-1 receptor agonists, such as liraglutide and semaglutide, tirzepatide has demonstrated superior efficacy in body weight control in several phase III clinical trials, with average weight reductions exceeding 20% in some study populations (15)
2025
While GLP-1 drugs can result in 15-25% total body weight loss, surgery often achieves 25-35% or more, with higher rates of long-term maintenance and remission of related diseases
It is a growth hormone-releasing hormone analog without DAC modification, designed for shorter half-life and rapid biological onset
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