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[18] [19] Some users report headaches or fatigue during the adjustment period, though there is limited evidence establishing a causal relationship between these symptoms and probiotic use
Similarly, the other incretin hormone, GIP is efficiently cleaved by DPP-4 in vivo (40), and DPP-4 inhibition increases intact GIP levels and enhances its effects (41)
K., & Pisklak, D
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This binding triggers a cascade of effects: delayed gastric emptying, reduced glucagon secretion, enhanced insulin sensitivity, and most importantly for weight loss, decreased food intake through central appetite suppression (Wilding et al., NEJM, 2021)
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