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Through TGR5 receptor activation, it inhibits STAT3/NF-B/MAPK pathway activation, reduces pro-inflammatory cytokine release, and improves cardiac function parameters at 100 mg/kg doses (Wang et al., 2025)

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recently employed complementary in vitro and in vivo methods to examine how altered MET signaling impacts synaptic development, observing an opposite effect on neuronal morphology in a stage-dependent way

Ruan et al., 2020