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Skin thinning or rebound hyperpigmentation Prolonged or improper use of certain topical agents, such as hydroquinone, may weaken the skin barrier or overstimulate melanin production, leading to uneven pigmentation

Strinic D, Petrovic A, Balenovic D, et al

Traditionally, mechanistic research on SCFA-mediated GLP-1 secretion, particularly for butyrate, has centered on cell membrane receptor pathways (e.g., GPR41/43/109a) or epigenetic regulation (HDAC inhibition) (Tolhurst et al., 2012

Semaglutide | Drugs BNF NICE

Talk with your doctor for advice if you believe you may benefit from vitamin B12 supplements or injections.