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GHK-Cu moves through the epidermis into the dermis, where copper peptide research focuses on skin appearance

StatPearls [Internet], 2024 Jan Avinoam Shiran, Eric Remer, Ihab Asmer, Basheer Karkabi, Eran Zittan, Aliza Cassel, Mira Barak, Orit Rozenberg, Khaled Karkabi, Moshe Y Flugelman

This paper presents gene profiling data relevant to GHKs effects on stem cells function

Bioavailability following subcutaneous injection is estimated at approximately 80%, substantially higher than oral administration, where peptide degradation in the gastrointestinal tract limits systemic exposure

Your skin has more adjusting to do, and purging may be more pronounced