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Invest 79 , 616619 (1987)

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demonstrated that GLP-1/GLP-1R signalling plays a crucial role in activating signal transducer and activator of transcription 3 (STAT3), which directly promotes human M2 macrophage polarization while inhibiting classically activated M1 macrophages, known for their pro-inflammatory and tissue-destructive properties (44)

Beyond its antioxidant properties, glutathione has been promoted for skin whitening primarily through oral supplements and intravenous injections Mechanism for Skin Lightening Glutathione affects skin pigmentation through multiple pathways

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