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Memory (escape latency in the Morris water maze test), neurotransmitters (acetylcholine, dopamine, gamma-amino butyric acid (GABA)), and neurochemicals (BDNF, catalase, glutathione, Amyloid Beta and cyclic GMP) were analyzed from whole brain samples in young (8-weeks-old) and aged (16-months-old) rats following 12 days of supplementation (100 mg/d HED of 1-MX [UPLEVEL, Ingenious Ingredients L.P., Lewisville, TX, USA]) via oral gavage

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Freezing reconstituted ipamorelin at -20C can extend stability beyond the standard 28-day refrigerated window to approximately 90 days, but each freeze-thaw cycle introduces mechanical stress that damages peptide structure, causing 812% degradation per cycle

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Blood 68 , 627632 (1986)