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Mechanisms of cardiorenal effects of sodium-glucose cotransporter 2 inhibitors: JACC state-of-the-art review
Curious how other clinicians are successfully tapering GLP-1 doses for their patients
Notably, in Kras G12D murine models, inflammatory stimuli accelerate early pancreatic neoplastic transformation through the activation of mTORC1 and mTORC2 complexes, which promote Arp2/3 complex-mediated actin reorganization to synergize with Kras G12D -driven ADM progression in vivo and in vitro [379]
Timing and dosing should be guided by clinical context
Ketamine action on astrocytes provides new insights into rapid antidepressant mechanisms
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