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Due to the fact that AMPK promotes glucose and lipid homeostasis, the current findings suggest that AMPK-activating agents (metformin, SGLT2i, GLP1-RAs) may certainly help patients with type 2 diabetes

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Catts SV, Shelley AM, Ward PB, Liebert B, McConaghy N, Andrews S et al (1995)

In many cases, insurance plans require prior authorization, meaning a healthcare provider must submit documentation to demonstrate that the drug is medically necessary

Thats true, but were using them at higher doses more recently for weight than they were used originally for diabetes