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There is limited evidence suggesting that changes to gut motility may influence the intestinal microbiota, though a direct causal relationship between semaglutide and microbiome disruption has not been firmly established
Sleep quality reaches its new baseline, typically significantly better than before treatment began
Astrocytic reactivity reflects activation of complex molecularly defined programmes which define remodelling of biochemical, morphological, metabolic, and physiological properties of astroglia leading to an upregulation or loss of homoeostatic cascades, or in gain of new protective or regenerative functions
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When used as a treatment, it is administered via intravenous infusion for a few days during each chemotherapy cycle, although the dosing regimen has varied in clinical trials (Loprinzi, Hershman 2020)
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