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Methods An extensive and systematic literature search was conducted over a 3-month period, from April 2024 to June 2024
Regular follow-up consultations are recommended to monitor progress and make any necessary adjustments
Research has demonstrated that GLP-1RAs significantly inhibit the expression of MMP-2 and MMP-9 in the human ovarian cancer cell line SKOV-3 within a TNF--induced inflammatory microenvironment, while simultaneously upregulating the levels of their inhibitors, tissue inhibitors-1 (TIMP-1) and tissue inhibitors-2 (TIMP-2) [78, 87]
CV risk factors were prevalent: 71% had a history of hypertension, 60% had hyperlipidaemia, and 14% reported current smoking
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