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It has been reported that the AUC 0- and C max of a single 2 mg oral dose of repaglinide were 105.9 ngh/mL and 60.3 ng/mL, respectively, for wild type ( *1/*1 ) CYP2C8, and 72.4 ngh/mL and 38.5 ng/mL for *3/*3 CYP2C8, respectively, and the plasma concentration decreased due to metabolic activation [17]
6, June 2017, pp
It is currently being evaluated in clinical trials
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[4] In case of accidental large overdose (e.g., someone receives far more frequent injections than prescribed), monitoring for symptoms like flushing, tingling in extremities, or liver enzyme elevations would be prudent
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