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As IL-1 has known effects on hypothalamic biogenic amines, the main source of corticotropin-releasing factor (CRF), it can regulate on pituitary ACTH and promote the production and release of cortisol (80), which may be the underlying mechanism of the HPA axis activation by IL-1

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Longtime talk show host Oprah Winfrey is opening up about her recent weight-loss success after sticking to a GLP-1 (glucagon-like peptide-1)