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Although most guidelines continue to recommend metformin as first-line anti-hyperglycemic therapy, the European Society of Cardiology [52] recommends that GLP-1RA or SGLT2i should be first-line therapy in individuals with ASCVD or at high or very high CV risk
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Currently, Retatrutide is only available through clinical trials
GLP-1 also affects these factors (except sex and medication)
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