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10.1002/jor.20089 85 StrangS
It should be noted that higher dosages of vitamin B12 may be necessary when treating this population
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These lipidation and amino acid substitutions solve two fundamental problems with native human amylin: its extremely short plasma half-life (measured in minutes) and its well-documented tendency toward amyloid fibril formation
The mechanism involves upregulation of matrix metalloproteinases (MMPs) and their inhibitors, which remodel collagen in a more organized way than unassisted healing
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