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Several studies have highlighted the capability of targeting the PERK axis to reprogram MDSCs from immunosuppressive to antitumoral phenotype [62]
Mitochondria are the site of a range of chemical reactions, including the tricarboxylic acid (TCA) cycle and ETC, and are responsible for the generation of electron carriers, adenosine triphosphate (ATP) and other biosynthetic molecules 29
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C-reactive protein predicts outcome in COVID-19: is it also a therapeutic target
doi:10.1016/S0140-6736(14)61682-2
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