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2.Phentermine suppresses appetite, while semaglutide slows gastric motility, reduces hunger, and improves insulin sensitivity

Weight fluctuates by 2 to 5 pounds daily due to water, food volume, and hormonal shifts

Retatrutide also shows meaningful improvements in metabolic markers beyond weight

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When you stop taking the medication, its appetite-regulating effects disappear, and the weight often comes back quickly