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Metformin-induced vitamin B12 deficiency can cause or worsen distal symmetrical, autonomic and cardiac neuropathy in the patient with diabetes

They should instead be educating patients on the risk benefit and suggesting behavioral changes to lose the weight

Navigating Insurance Coverage and Reimbursement Public health coverage is very different across Europe: In some countries (such as Denmark and, in some cases, France), public healthcare may cover part of the cost for certain patients In many countries (such as Germany, Spain, and Italy), most people have to pay the full cost unless they are being treated for type 2 diabetes Even when public coverage is feasible, obtaining approval can be a lengthy and complex process

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