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Available sizes include 100 mg, 50 mg, subject to live stock

IGF-1 also binds to the insulin receptor and activates it, thereby encouraging cells to take up glucose from the blood stream

Pros of GLP-1s: Non-surgical option Can lead to 1520% body weight loss in clinical trials May improve blood sugar, cholesterol, and inflammation Weekly injections, often self-administered Cons of GLP-1s: Real-world weight loss may be lower than clinical trials (510%) Side effects include nausea, vomiting, fatigue, and gastroparesis High cost and limited insurance coverage Weight may return if medication is stopped What is weight loss surgery

Learn more about the OSA pathway Coming mid-2026: Medicare will cover Zepbound for obesity with comorbidities at a $50/month copay, following a November 2025 deal with Eli Lilly

If you are finding one medication difficult to tolerate, switching is a clinical option worth discussing with your prescriber