Previous studies have reported that sAC acts as a physiological ATP sensor in glucose-responsive cells, with sAC-generated cAMP reflecting intracellular ATP levels (40)
Dietary taurine, creatine, carnosine, anserine and 4-hydroxyproline are beneficial for preventing and treating obesity, cardiovascular dysfunction, and ageing-related disorders, as well as inhibiting tumorigenesis, improving skin and bone health, ameliorating neurological abnormalities, and promoting well being in infants, children and adults
J Biol Chem 294:1477614802
While optimizing diabetes control may indirectly support cognitive health through improved metabolic and vascular parameters, patients should discuss treatment decisions with their healthcare provider based on established evidence and individual health needs
Although studies in animal models have shown that GLP-1R agonists reduce Aaccumulation and tau hyperphosphorylation, few human studies have evaluated these effects