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Following gastrointestinal disorders, the most common adverse events were administration site reactions

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doi: 10.1002/adfm.201103007

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BBR ameliorates ovarian inflammatory responses in PCOS rat models through downregulating TLR4/lyn tyrosine kinase (LYN)/NF-B signaling and suppressing pro-inflammatory mediators (TNF-, IL-1, IL-6) via PI3K/Akt/NF-B pathway regulation, thereby suppressing immune cell infiltration and cytokine storm cascades [191]

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