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These effects are dose-dependent and transient, typically normalizing within hours

This matters for the hypermobility community because many people with EDS and hypermobility develop OA-type joint changes earlier in life due to the chronic mechanical stress of unstable joints, and the overlap between fibromyalgia and osteoarthritis is well-recognised

Without immediate treatment, this condition can be life threatening

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Notably, higher body mass index (BMI) has been linked to a lower risk of depression among older adults, which contrasts with observations in younger populations