A small, phase 2 crossover trial of DMQ versus placebo found significantly improved bulbar function as measured by the patient-reported CNS-BFS, as well as the bulbar subdomain of the ALSFRS-R [186]
GLP-1 agonists and dual GIP/GLP-1 agonists work best alongside a healthy lifestyle
And if regulators focus only on whether peptides fit neatly into traditional drug categories, they may miss the bigger public health problem entirely
Hormonal influences, reproductive demands, and autoimmune conditions affecting gastric absorption (e.g., pernicious anemia, thyroid disease) may predispose women to deficiency, while greater health-seeking behavior increases test frequency
Neville BW, Damm DD, Allen AM, Chi AC