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The poor bioavailability of exogenous SODs has been criticized
BigioBMathAASousaVCZelliDSvenningssonPMcewenBSet al
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& Sun, L
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In the early years of GLP-1 RA use it was suggested, an increased risk of pancreatitis and pancreatic tumors related to the use of these anti-diabetics.26 However, large clinical trials and other subsequent studies did not confirm this finding accordingly, the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA) concluded that a causal relationship between these drugs and the development of pancreatitis or pancreatic cancer could not be established.2731 Our study has several limitations
