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Their diverse biological effects, coupled with a growing body of preclinical and clinical evidence, support the potential for GLP-1R agonists to be integrated into multidisciplinary pain management protocols

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Epitalon has been shown to increase IL-2 mRNA expression in both human in vitro and animal in vivo studies, but its effects appear especially pronounced in aged tissues [4, 48], pointing toward a role in immunorejuvenation rather than broad immunostimulation