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Mitochondrial ROS production and oxidative mtDNA damage is increased during reoxygenation in the GPX1 knockout mice, in addition to structural abnormalities in cardiac mitochondria and myocytes, suggesting GPX1 may play an important role in protecting cardiac mitochondria from reoxygenation damage in vivo

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The three things that help maintain muscle mass during weight loss are: losing weight slowly at a rate of around 1lb per week, eating around 1.2 to 1.6 grams of protein per kg of body weight per day (a serving the size of the palm of your hand at each meal), and adding resistance training a couple of times a week