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The direct liposomal form provides an immediate boost while NAC supports ongoing endogenous synthesis

The combination group showed significantly higher improvement scores than the dermaroller-only group at baseline and Week 3, with p-values indicating statistically significant differences

Under unfolded protein stress conditions, GRP78 binds to unfolded or misfolded proteins and subsequently activates downstream ER stress sensors, including IRE1, PERK, and ATF6, to trigger a response to unfolded proteins (Yoboue et al., 2017) , (Wei et al., 2012)

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Nature Med