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Oral semaglutide at doses of up to 14 mg daily is approved for T2D and doses as high as 50 mg daily have been evaluated for weight loss, with 25 mg daily filed for approval for the treatment of obesity
These medications have been extensively studied in large-scale clinical trials and are licensed by the MHRA for specific indications including type 2 diabetes and, in some cases, weight management, as outlined in NICE guidance (NG28)
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