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Modulation in the expression profile of various GR isoforms have been known to occur under various stress conditions (reviewed in Yousuf et al., 2012
What makes this antioxidant it so powerful is its presence in every type of cell, including the immune system
This process happens in tissues throughout the body, meaning NAC-derived glutathione synthesis occurs at the cellular level where it is needed, not just in the blood
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Haem oxygenase is up-regulated by numerous other stressors that share a capacity to decrease tissue GSH
