In one trial, adults who lost weight on tirzepatide for 36 weeks were switched to a placebo and followed for another year
Metabolic Support: More muscle means a higher resting metabolic rate, aiding long-term fat-loss maintenance
[1] Understanding these foundational mechanisms helps contextualize questions about whether the body develops tolerance to tirzepatide's effects over extended periods of use
Center SA, Warner KL, Randolph JF, Sunvold GD, Vickers JR: Influence of dietary supplementation with (L)-carnitine on metabolic rate, fatty acid oxidation, body condition, and weight loss in overweight cats
It is critically important that new treatments are tested on people and in the situation where they are intended to be used